Fractionated electrograms with ST-segment elevation recorded from the human right ventricular outflow tract
نویسندگان
چکیده
From the *L’Institut de RYthmologie et de modélisation Cardiaque (LIRYC), Fondation Bordeaux University, Pessac, France, University of Bordeaux, IMB, UMR 5251, Talence, France, Department of Biomedical Engineering, George Washington University, Washington, DC, xDepartment of Medicine and Developmental Biology, Washington University in St Louis, St Louis, Missouri, kDepartment of Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, and {Department of Medical Biology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
منابع مشابه
ST-Segment Elevation and Fractionated Electrograms in Brugada Syndrome Patients Arise From the Same Structurally Abnormal Subepicardial RVOT Area but Have a Different Mechanism.
BACKGROUND Brugada syndrome (BrS) is characterized by a typical ECG pattern. We aimed to determine the pathophysiologic basis of the ST-segment in the BrS-ECG with data from various epicardial and endocardial right ventricular activation mapping procedures in 6 BrS patients and in 5 non-BrS controls. METHODS AND RESULTS In 7 patients (2 BrS and 5 controls) with atrial fibrillation, an epicard...
متن کاملLocal activation delay exacerbates local J-ST elevation in the epicardium: Electrophysiological substrate in Brugada syndrome
Introduction The mechanisms of J-ST elevation in the right precordial leads in patients with Brugada syndrome (BrS) remain controversial (ie, repolarization vs depolarization hypotheses). Recently, epicardial substrate ablation for late fractionated potentials and a low-voltage area (LVA) in the right ventricular outflow tract (RVOT) has been performed for ventricular fibrillation (VF) that is ...
متن کاملCardiac electrophysiological substrate underlying the ECG phenotype and electrogram abnormalities in Brugada syndrome patients.
BACKGROUND Brugada syndrome (BrS) is a highly arrhythmogenic cardiac disorder, associated with an increased incidence of sudden death. Its arrhythmogenic substrate in the intact human heart remains ill-defined. METHODS AND RESULTS Using noninvasive ECG imaging, we studied 25 BrS patients to characterize the electrophysiological substrate and 6 patients with right bundle-branch block for compa...
متن کامل[Comparison of epicardial fat thickness in diabetic patients compared to non-diabetics with acute myocardial infarction and ST-segment elevation (AMI-STEMI)].
INTRODUCTION Visceral fat has deleterious metabolic effects and has been associated with myocardial ischemia. OBJECTIVE To compare epicardial fat thickness in diabetic versus non-diabetic patients with acute myocardial infarction with ST-segment elevation. MATERIAL AND METHODS We performed a cross-sectional study in 60 patients with acute myocardial infarction with ST-segment elevation (30 ...
متن کاملThe electrophysiologic mechanism of ST-segment elevation in Brugada syndrome.
OBJECTIVES We sought to demonstrate the electrophysiologic (EP) mechanism of the ST-T change in Brugada syndrome. BACKGROUND Brugada syndrome is characterized by various electrocardiographic manifestations (e.g., right bundle branch block, ST-segment elevation, and terminal T-wave inversion in the right precordial leads) and sudden cardiac death caused by ventricular fibrillation. Direct evid...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2017